This is book number 1 in the Honor Harrington (Audio) series.
Having made a superior look a fool, Honor Harrington has been exiled to Basilisk Station in disgrace and set up for ruin.
Her demoralized crew blames her for their ship's humiliating posting to an out-of-the-way picket station.
The aborigines of the system's only habitable planet are smoking homicide-inducing hallucinogens.
Parliament isn't sure it wants to keep the place; the major local industry is smuggling; the merchant cartels want her head; the star-conquering, so-called "Republic" of Haven is up to something; and Honor Harrington has a single, over-age light cruiser with an armament that doesn't work to police the entire star system.
But the people out to get her have made one mistake. They've made her mad.